Clomipramine
(kloe-mi-pra-meen)
Description: Tricyclic Antidepressant; Behavior Modifiying Agent
Other Names for this Medication: Clomicalm®, Anafranil®
Common Dosage Forms: Veterinary: 5 mg, 20 mg, 40 mg, & 80 mg tablets

How is this medication useful? Veterinarians may prescribe clomipramine in dogs and cats for a variety of behavior problems such as dominance aggression (ie, threatening behavior/actions), separation anxiety (ie, petfeels anxious when itis away from you), or obsessive-compulsive behaviors (eg, excessive grooming, pacing). In cats, clomipramine can also treat behaviors such as urine spraying, aggression (ie, threatening behavior/actions) toward other cats or humans and compulsive behaviors (eg, grooming, wool-sucking). The FDA (U.S. Food & Drug Administration) has approved this drug (Clomicalm®) for treatment of separation anxiety in dogs that are atleast 6 months of age. The FDA allows veterinarians to prescribe and use products containing clomipramine in other animal species in certain situations. In some countries, clomipramine is approved for use in cats. You and your veterinarian can discuss why this drug is the most appropriate choice.

Common, but not serious, side effects include:
Drowsiness (ie, sleepiness). Vomiting, diarrhea, constipation, or loss of appetite. Dry mouth. Increased thirst. Trouble urinating. You don’t have to be overly concerned if you see any of these signs unless they are severe, are persistent, or worsen. Contact your veterinarian if this happens.

If you have any other questions about this medication, contact your veterinarian or pharmacist.