PROIN^® Chewable Tablets (phenylpropanolamine hydrochloride)

The Only FDA Approved Phenylpropanolamine Hydrochloride Medication For The Treatment Of Urinary Incontinence Due To Urethral Sphincter Hypotonus.

Treat your dog's incontinence and urine leakage with liver-flavored PROIN (phenylpropanolamine hydrochloride), FDA approved for control of canine urinary incontinence due to week urethral sphincter muscle tone.

Urethral sphincter hypotonus causes canine urinary incontinence as a result of weakened muscles of the urethral sphincter.

This product is made by PRN Pharmacal.

 

What are the common clinical signs of urinary incontinence in dogs?

• Dripping or leaking urine
• Excessive licking of the genital area
• Red and irritated skin around the genital area
• Needing to go more frequently than normal
• Wetting the bed or sleeping area
• Urinating inappropriately in the house

Fortunately, while frustrating at first, canine urinary incontinence may be controlled with PROIN^®, a safe and effective FDA-approved chewable tablet that works by increasing urethral sphincter tone to help prevent urinary accidents.

 

PROIN^® works by increasing urethral sphincter muscle tone to help prevent urinary accidents.

 

 

Why Proin?

• Only FDA approved PPA for the treatment of urinary incontinence due to urethral sphincter hypotenuse with proven efficacy.
• Offers three tablet strengths of half scored, liver-flavored tablets allowing health care providers to tailor the dosage for most dogs.
• Formulated as a liver-flavored tablet to help make dosing easier.

 

How to use Proin Chewable Tablets?

 

For oral use in dogs only. Not for human use. Keep out of reach of children. If accidentally ingested by humans, contact a physician immediately.

 

Always follow the dosage instructions provided by your veterinarian. Give as late in the evening as possible to prevent accidents during the night. May take several days of treatment before urinary incontinence improves. Usually need to treat long term, but some pets may only need to be treated for several months or seasonally. 

 

The safe use of PROIN in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. 

 

How does Proin Chewable Tablets work?

 

Proin works by increasing the tone of the urethral sphincter, which helps to control urine leakage.

 

Active Ingredients:

• Phenylpropanolamine
• Liver flavor
• Does not contain any beef or beef products

Supplied:

Flavored Chewable Tablets

• 25 mg/60 ct. 25 mg/180 ct.
• 50 mg/60 ct. 50 mg/180 ct.
• 75 mg/60 ct. 75 mg/180 ct.

Side Effects:

The most commonly reported side effects were:

• vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink).
• Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported.
• In some cases death, including euthanasia has been reported. Sudden death was sometimes preceded by vocalization or collapse.
• PROIN may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure.
• Proin may include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite.

Important Safety Information:

This medication should not be used in animals allergic to it. Do not use in animals with glaucoma, enlarged prostate, hyperthyroidism, diabetes, heart problems or high blood pressure. Do not use in pregnant or nursing animals. Do not give this medication with ephedrine or epinephrine and do not give within 2 weeks of using a monoamine oxidase inhibitor (MAOI) such as selegilene. Use caution when this medication is given with digitalis, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as propranolol. Always tell your veterinarian and pharmacist what other medications your pet is taking.